A History of Immunology by Arthur M. Silverstein

By Arthur M. Silverstein

It is a professional-level highbrow background of the advance of immunology from approximately 1720 to approximately 1970. starting with the paintings and insights of the early immunologists within the 18th century, Silverstein lines the advance of the most important principles that have shaped immunology right down to the maturation of the self-discipline within the decade following the second one global battle. Emphasis is put on the philosophic and sociologic weather of the medical milieu within which immunology has built, supplying a historical past to the extensive tradition of the self-discipline.

Key Features
* A professional-level highbrow heritage of the improvement of immunology from approximately 1720 to 1970, with emphasis put on the social weather of the medical milieu within which smooth immunology evolved
* Written through an writer rather well recognized either as a historian of scientific technological know-how and for his great study contributions to the immunopathology of the eye
* the single entire background of immunology on hand

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But finally, in late April of 1721, the young Montagu child was successfully inoculated. When the pocks appeared, three members of the College of Physicians examined her separately, and one of them was so convinced by what he saw that he had Maitland inoculate his own son, the only one of his children who had not yet already succumbed to the disease. T h e impact of Lady Mary's demonstration of inoculation on the events that followed is not entirely clear. Undoubtedly it aroused considerable professional interest, although it was not reported in the newspapers of that time.

The humoralists were predominantly German and followed the leadership of Robert Koch and his disciples at Koch's Institute in Berlin. An examination of the history of the cellular-humoral dispute illustrates several interesting points. First, it provides the historian of ideas with yet another example of how earlier and even outmoded concepts help to determine the structure and content of future thought and how the intransigent commitment to a scientific dogma often prevents timely and rational compromise.

12, p. 2134 (1721); Weekly J. or Br. Gazetter Aug. 12, p. 1999 (1721); Weekly J. or Saturdafs-Post Aug. 12, p. 844 (1721). The Royal Experiment on Immunity, 1721-1722 37 25. R. Mead, A Discourse on the Small Pox and Measles, pp. 88-89. John Brindley, London, 1748. 26. Reference 15, p. 20. 27. London Gaz. Mar. 6-10, No. 6040 (1722). 28. Sloane MSS, MS. 4076, f. 331, Mar. 14, British Museum, London, 1722. 29. J. G. -Book R. Soc. XIII, Mar. 27, 319 (1729). 30. B. " London, 1759. [Reprinted in L. H.

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