A History of Modern Immunology. The Path Toward by Zoltan A. Nagy

By Zoltan A. Nagy

A heritage of recent Immunology: A course towards Understanding describes, analyzes, and conceptualizes a number of seminal occasions and discoveries in immunology within the final 3rd of the twentieth century, the period while so much questions about the biology of the immune approach have been raised and likewise came across their solutions. Written through an eyewitness to this background, the ebook offers perception into own elements of the $64000 figures within the self-discipline, and its info pushed emphasis on knowing will profit either younger and skilled scientists.

This ebook offers a concise advent to themes together with immunological specificity, antibody variety, monoclonal antibodies, significant histocompatibility advanced, antigen presentation, T telephone biology, immunological tolerance, and autoimmune affliction. This huge history of the self-discipline of immunology is a precious significant other for college students of immunology, study and medical immunologists, and learn managers within the pharmaceutical and biotechnology industries.

    • Contains the historical past of significant breakthroughs in immunology featured with authenticity and insider details
    • Gives an perception into own facets of the gamers within the historical past of immunology
    • Enables the reader to acknowledge and choose info of heuristic price which elucidate vital points of the immune system
    • Provides sturdy examples and directions for the popularity and choice of what's very important for the exploration of the immune system
    • Gives transparent separation of descriptive and interpretive components, permitting the reader to tell apart among proof and research supplied by way of the author

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    Scand. J. Immunol. 2004;60:3. Sercarz EE, Maverakis E. Mol. Immunol. 2004;40:1003. Sercarz EE, Cohen IR. Mol. Immunol. 2004;40:983. Cohn M. Mol. Immunol. 2005;42:651. Meloen RH, Puijk WC, Sloostra JW. J. Mol. Recognit. 2000;13:352. Monzavi-Karbassi B, Cunto-Amesty G, Luo P, Shamloo S, Blaszcyk-Thurin M, Kieber-Emmons T. Int. Immunol. 2001;13:1361. 1 DISCOVERY The clonal selection theory has predicted that a single B cell and its descendants would produce one single antibody both as a cell surface receptor and in secreted form.

    Exp. Cell Res. 1970;60:61. Cotton RG, Milstein C. Nature 1973;244:42. Schwaber J, Cohen EP. Proc. Natl. Acad. Sci. USA 1974;71:2203. Jerne NK, Nordin AA. Science 1963;140:405. Köhler GK, Howe SC, Milstein C. Eur. J. Immunol. 1976;6:292. Köhler GK, Milstein C. Eur. J. Immunol. 1976;6:511. Kearney JF, Radbruch A, Liesegang B, Rajewsky K. J. Immunol. 1979;123:1548. Oi VT, Jones PP, Goding JW, Herzenberg LA, Herzenberg LA. Curr. Top. Microbiol. Immunol. 1978;81:115. Ledbetter JA, Herzenberg LA.

    Meloen RH, Puijk WC, Sloostra JW. J. Mol. Recognit. 2000;13:352. Monzavi-Karbassi B, Cunto-Amesty G, Luo P, Shamloo S, Blaszcyk-Thurin M, Kieber-Emmons T. Int. Immunol. 2001;13:1361. 1 DISCOVERY The clonal selection theory has predicted that a single B cell and its descendants would produce one single antibody both as a cell surface receptor and in secreted form. 1). However, a direct proof entailing the isolation and expansion of single B cells and investigation of the antibody they secrete was difficult to obtain.

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