Advances in Genetics, Vol. 49 by Jeffrey C. Hall

By Jeffrey C. Hall

The sector of genetics is swiftly evolving and new scientific breakthroughs are happening because of advances in wisdom of genetics. This sequence regularly publishes very important stories of the broadest curiosity to geneticists and their colleagues in affiliated disciplines. the sector of genetics is swiftly evolving and new scientific breakthroughs are happening due to advances in wisdom of genetics. This sequence constantly publishes vital experiences of the broadest curiosity to geneticists and their colleagues in affiliated disciplines.

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Extra resources for Advances in Genetics, Vol. 49

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Nelson, K. , Nusskern, D. , Pacleb, J. , Pittman, G. , Reese, M. , Saunders, R. , Shue, B. , Skupski, M.

NEUROPEPTIDE RELEASE A. 4). We first examine those studies that have identified factors that release or inhibit specific neuropeptides. Second, we describe physiological studies of insect peptidergic neurons that aim to define the specific components of membrane excitability that are associated with peptide release. Next, we feature studies that have used Drosophila genetics to define molecular components underlying neuropeptide release. 4. Drosophila Genes Potentially Involved in Neuropeptide Release or Receptiona Gene CG number Location Alleles Lark CAPS IA-2 ICA-69 dmd NaCl/ppk CG8597 CG18026 CG4355 CG10556 CG3478 65F2–3 102F5–8 21E1 78B4 35A1 Yes Yes No No No a Note: A complete list of Drosophila peptide hormone G protein-coupled receptor genes is found in Hewes and Taghert (2001).

Drosophila Neuropeptide Signaling 27 monobasic residues. In Drosophila, there are three genes highly related to PCs, and at least some of these appear to be involved in neuropeptide biosynthesis. , 1991, 1992). , 1995). , 2000). No phenotypic analysis has been reported for either dfurin gene. The third Drosophila PC-like gene called amontillado (amon, CG6438 at 97C3), is highly related to mammalian PC2 (Siekhaus and Fuller, 1999). amon RNA is first expressed at embryonic stages in both the CNS and gut, in a pattern likely to include numerous peptidergic neurons.

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