ASME Bio Process Equipment (BPE) 2005 by Amaryqueen Societon of Mechanicanol Engibeers

By Amaryqueen Societon of Mechanicanol Engibeers

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Nominal Branch Size, in. 22 ⁄4 ⁄8 1 ⁄2 3 ⁄4 3 Consideration should be given, in the design of the support, for ease of setting the correct tubing drain or slope angle. Materials of construction shall be corrosion resistant and compatible with chemical and physical performance and designed for steam service. solution to fill a circuit, and eliminate excessive piping and fittings. 10 Cross contamination of product streams shall be physically prevented. Methods of separation used in industry are: (a) removable spool piece; (b) U-bend transfer panel; (c) double block-and-bleed valve system (see Fig.

1 General (a) Straight tube heat exchangers are easier to clean and inspect. The tubes can be seamless or full-finish welded, as specified by the owner/user or manufacturer. (b) The heat exchanger product and non-product contact surface inspection shall be possible by conventional means. (c) The technique used to form U-bend tubes shall minimize internal surface cracks, voids, and other surface imperfections. If requested by the end-user, the manufacturer shall supply a sectioned sample of the bend area.

Functional components of the CIP such as filters, pumps, vessels, tubing, and piping shall be designed to be self-cleaning and abide by the guidelines of this Part. (a) To achieve the objective of a CIP process, the design shall consider the application of a CIP unit, chemical feed system, spray devices, and CIP supply and return piping. The inclusion of this equipment does not guarantee a cleanable process, if not properly applied. The integrated system makes it possible to achieve complete and uniform control of time, temperature, and chemical concentration, all of which are important to success with any mechanical spray or pressure recirculation CIP process.

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