CD100/Sema4D by Kumanogoh A., Kikutani H.

By Kumanogoh A., Kikutani H.

Show description

Read Online or Download CD100/Sema4D PDF

Best immunology books

Human Antibody Therapeutics For Viral Disease (Current Topics in Microbiology and Immunology)

Even supposing the software of human antibodies as clinical therapeutics for melanoma and immune illnesses has been well-established, it's only starting to be learned for the therapy of viral infectious illnesses. Polyclonal immunoglobulins have lengthy been used for a few viral illnesses, yet they've got constrained efficiency and ailment scope.

The Tumor Immunoenvironment

Research of multidirectional immunological responses on the tumor web site permits forming a brand new notion of The Tumor Immunoenvironment, that is brought and mentioned within the current e-book with a selected specialise in the position of immune cells in controlling the tumor microenvironment at assorted levels of melanoma improvement.

Antibodies in cell biology

Antibodies in cellphone Biology specializes in a brand new new release of protocols geared toward the mobilephone biologist. This laboratory handbook positive factors structures and methods which are specially appropriate for contemporary difficulties. The contributing authors were conscientiously selected for his or her particular services, and feature supplied unique protocols, recipes, and troubleshooting publications in each one bankruptcy.

Additional info for CD100/Sema4D

Sample text

The interaction of the multivalent macromolecular antigens may, for steric reasons, not result in all receptor sites being occupied. lSS Moreover, in precipitin inhibition studies, as the hapten displaces more and more antigen from antibody sites, the antigen itself will begin to contribute to the formation of the soluble complexes. When competitive binding radioimmunoassay or enzyme immunoassay are carried out with antisera, which almost always contain a heterogeneous spectrum of antibodies, the dilutions used are generally so high that one is working with only the fraction of antibodies of highest affinity.

Biophys. Acta 251, 427 (1971). 1r5 E. Engvall and P. Perlmann, J. Immunol. 109, 129 (1972). 17e D. R. Hoffman, J. Allergy Clin. lmmunol. 51, 303 (1973). 32 PRINCIPLES [1] AND METHODS (4000-8000 cpm) and allowed to come to equilibrium; the bound ligand is separated from the free ligand, and the proportion of free or of bound ligand is determined. For the system to be suitable, the receptor protein if added in sufficient quantity should precipitate 90-100% of the added ligand as determined by counting or enzyme assay.

A. Kabat, J. lmmunol. 108, 1232 (1972). l e o D. G. Streefkirk and C. P. J. Glaudemans, Biochemistry 16, 3760 (1977). 161 K. Takeo and S. Nakamura, Arch. Bioehem. Biophys. 153, 1 (1972). lnu V. Horesjf, M. Tich~, and J. Kocourek, Bioehirn. Biophys. Acta 499, 290 (1977). le~ S. Sugii, K. Takeo, and E. A. Kabat, J. lmmunol. 17,3, 1162 (1979). ~ V. Horesjf, M. Tich~, and J. Kocourek, Trends Bioehem. Sei. 4, 6 (1979). [1] PRINCIPLES OF ANTIGEN--ANTIBODY REACTIONS 31 probably be difficult to use affinity electrophoresis with heterogeneous mixtures of antibodies.

Download PDF sample

Rated 4.06 of 5 – based on 22 votes