
By Dass S. Vinay, Byoung S. Kwon (auth.), Lieping Chen (eds.)
This complete quantity, written through specialists within the box, covers approximately all points of ongoing learn concerning the CD137 pathway. contemporary examine has proven that the manipulation of CD137 pathway molecules is particularly promising within the remedy of melanoma, viral an infection, transplantation rejection and autoimmune ailments in experimental animal versions. the amount contains examine with regards to the id and figuring out of practical results of CD137 receptor and ligand molecules which represents a huge attempt within the box of immunology. CD137 Pathway: Immunology and illnesses is a perfect booklet for immunologists, microbiologists, melanoma researchers, molecular biologists, biochemists, and pharmaceutical and biotechnology corporation scientists.
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Sample text
Curr. Opin. , 11, 286–293. , and Croft, M. (1998). Ox-40: Life beyond the effector T cell stage. Semin. , 10, 471–480. , and Chen, L. (2002). Cutting edge: Expression of functional CD137 receptor by dendritic cells. , 168, 4262–4267. , and Wu, H. (1999). The structure basis for the recognition of diverse receptor sequence by TRAF2. Mol. Cell, 4, 321–330. , and Sprent, J. (1998). Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity, 8, 591–599. , and Chen, A.
Exp. Med. 191, 1721–1734. B. (1990). Role of the CD28 receptor in T-cell activation. Immunol. Today, 11, 211–216. , and Tosato, G. (1996). Activation of na¨ıve and memory T cells by interleukin-15. Blood, 88, 230–235. Kenneth, A. , and Thompson, C. B. (2002). Activation and Inhibition of lymphocytes by costimulation. J. Clin. , 109, 295–299. E. (2000). The NF-κB cascade is important in Bcl-XL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J.
2000). The NF-κB cascade is important in Bcl-XL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J. , 165, 1743–1749. E. (2002). Role of 4-1BB (CD137) in the functional activation of cord blood. Blood, 100, 3253 and 3260. S. (1999). 4-1BB costimulation promotes human T cell adhesion to fibronectin. Cell. , 192, 13–21. R. (1992). Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature, 358, 70–73. S. (2002). New insights into the role of 4-1BB in immune response: Beyond CD8+ T cells.